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Our Research

The idea of a functional nonequilibrium nanotechnology capable of performing diverse functions ranging from energy storage, sensing, movement, synthesis, information processing and even thinking sounds like something from the pages of science fiction. Of course, a sophisticated nonequilibrium nanotechnology capable of performing all these things and more already exists: it is called biology.

We are interested in how nonequilibrium behaviour can be driven and sustained. Our work takes a 'kinetics first' approach, whereby understanding the fundamental kinetic models that drive complex newtorks allows us to build up interesting chemical systems. In doing so, we study phenomena such as 
nonequilibrium behaviour driven and sustained by ratchet mechanisms, feedback processes and emergent autocatalysis. We often explore such systems in the context of compartmentalised systems, that enable us to generate and harness transmembrane gradients as an convenient energy source. Ultimately, we hope to develop a better understanding of the emergent nonequilibrium processes, and apply these lessons in developing artificial nanotechnologies.

An understanding of the underlying theory is crucial to guiding our research on nonequiulibrium systems. See here for our groups first independent paper, which discusses how understanding the implications of the famous 19th century Maxwell's Demon thought experiment is crucial to the future development of transmembrane active transport processes. It also gave rise to our lab mascot!

Read a Chemistry World article by Anna Demming on Molecular Ratchets featuring an interview with Stefan

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Watch Stefan's Presentation on Molecular Ratchets to the Foresight Institute

Durham University

Department of Chemistry

Lower Mountjoy

Stockton Road

Durham DH1 3LE, UK

©2023 Stefan Borsley 

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